摘要亚临床甲状腺功能异常(STD)和骨质疏松是常见的内分泌疾病,主要发生在女性和老年人群中.甲状腺激素和促甲状腺激素可直接或间接影响骨代谢,导致骨密度发生变化.而STD患者体内这两种激素水平异常,提示STD和骨质疏松之间存在一定的联系.此外,外源性甲状腺激素替代治疗亦可影响骨代谢,导致骨密度下降和骨质疏松.因此,明确STD和骨质疏松之间的联系并采取适当干预措施对于预防STD患者发生骨质疏松有重要意义.
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abstractsBoth subclinical thyroid dysfunction (STD)and osteoporosis are common endocrine diseases which affect female and the elderly population mainly.Thyroid hormone and thyroid-stimulating hormone(TSH) can affect bone metabolism directly or indirectly,leading to changes in bone mineral density.Both thyroid hormone and thyroid-stimulating hormone are abnormd in STD patients which suggests an association between STD and osteoporosis.In addition,thyroid hormone replacement therapy may also affect bone metabolism,resulting in a reduction of bone mineral density and osteoporosis.Therefore,uncovering the relationship between STD and osteoporosis and taking appropriate intervention to improve the living quality of patients with STD are of great importance.
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