摘要甲状腺功能亢进症(甲亢)是循环中过多的甲状腺激素导致的以高代谢为主要表现的临床综合征，其在全球的发病率逐渐上升。血浆置换是严重甲状腺毒症的有效替代疗法，它通过去除与血浆蛋白结合的大分子物质来快速恢复甲状腺素水平，快速改善临床症状。其在临床上更多地用于治疗严重甲亢、不耐受抗甲状腺药物及甲状腺危象的患者。血浆置换导致的一些相关不良反应，亦需关注。

abstractsHyperthyroidism is a clinical syndrome characterized by hypermetabolism caused by excessive thyroxine in the circulation, and its global incidence is gradually increasing. Plasmapheresis is an effective alternative to severe thyrotoxicosis. It quickly restores the level of thyroxine and improves clinical symptoms by removing macromolecular substances that bind to plasma proteins. Plasmapheresis is more widely used in the treatment of severe hyperthyroidism, patients with intolerance of anti-thyroid drugs and thyroid storm. Some related adverse reactions caused by plasmapheresis should also be concerned.