摘要周细胞是血脑屏障的一种重要细胞成分,在脑微血管生成、内皮细胞紧密连接形成、血脑屏障分化、微血管动态运动和结构稳定性方面起调节作用.周细胞在一些疾病,如脑血管病、神经退行性疾病、神经免疫性疾病和外伤性脑损伤中,呈现很独特的功能特性.文章对周细胞在血脑屏障中的作用做了综述.
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abstractsPericytes are a very important cellular constituent of the blood-brain barrier.They play a regulatory role in brain angiogenesis,endothelial cell tight junction formation,blood-brain barrier differentiation,microvascular dynamic motion and structural stability.Pericytes exhibit unique functional characteristics in some diseases,such as cerebrovascular disease,neurodegenerative disease,neuroimmune disease and traumatic brain injury.This article reviews the roles of pericytes in the blood-brain barrier.
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