摘要目的 评价3 T磁共振血管造影(magnetic resonance angiography,MRA)在颅内动脉瘤血管内弹簧圈栓塞术后随访中的诊断价值.方法 检索PubMed、EMbase、Cochrane数据库以及CBM、CNKI和VIP等数据库,按照诊断试验的纳入标准,筛选有关MRA在颅内动脉瘤血管内弹簧圈栓塞术后随访诊断价值的诊断试验,采用QUADAS条目评价纳入研究的方法学质量,并采用Meta-Disc1.4软件进行汇总分析,绘制受试者工作特征曲线并计算曲线下面积,评价MRA诊断颅内动脉瘤栓塞术后残留的敏感性和特异性.结果 共纳入6项研究,包括253例患者,3TMRA诊断颅内动脉瘤残留的合并敏感性为0.915(95％可信区间0.850～0.959),合并特异性为0.847(95％可信区间0.787 ～0.896),受试者工作特征曲线下面积为0.951,Q=0.892.结论 3 T TOF MRA可作为颅内动脉瘤栓塞术后一种有效和可行的影像学随访方法,但限于方法学的局限性,还需要高质量的研究进一步验证MRA在颅内动脉瘤栓塞术后随访中的应用价值.

abstractsObjective To evaluate the follow-up diagnostic value of 3 T magnetic resonance angiography (MRA) after intracranial aneurysm coil embolization.Methods The databases such as PubMed,EMbase,Cochrane Library,CBM,CNKI and VIP were retrieved.According to the inclusion criteria of diagnostic tests,the diagnostic tests of the follow-up diagnostic value about MRA were screened after intracranial aneurysm coil embolization.The methodological quality included in the studies was evaluated using QUADAS items and the meta-analysis was conducted using Meta-Disc 1.4 software.The receiver operating characteristic curve was drawn and the area under the curve was calculated.The residual sensitivity and specificity diagnosed by MRA after intracranial aneurysm embolization were evaluated.Results A total of 6 studies were included,including 253 patients.The pooled sensitivity and specificity in 3 T MRA diagnosing residual intracranial aneurysms were 0.915 (95％ confidence interval [ CI]0.850 - 0.959) and 0.847 (95％ CI 0.787 - 0.896) respectively.The area under the receiver operating characteristic curve was 0.951,Q =0.892.Conclusions 3 T TOF MRA can be used as an effective and feasible imaging follow-up method after embolization of intracranial aneurysms,however,because of the methodological limitations,the high-quality research is needed to further validate the application value of the MRA during follow-up after intracranial aneurysm embolization.