摘要反常性痤疮是一种慢性复发性炎症性疾病,女性多发,主要累及腋窝、腹股沟、肛周等顶泌汗腺部位,其病因和发病机制尚不清楚,与遗传因素、毛囊改变、细菌感染、免疫因素、性激素、吸烟和肥胖等多种因素相关.治疗的主要方法包括抗生素、维A酸、性激素、肿瘤坏死因子拮抗剂、激光和手术治疗.为了更好地防治反常性痤疮,概述近年来该病发病机制和治疗方面的研究进展.

abstractsAcne inversa (AI) is a kind of chronic recúrrent inflammatory disease.Females are more likely to be affected by AI than males.Apocrine gland-bearing areas including axillary,inguinal,perianal,and perineal regions are commonly involved.The etiology of AI is unknown,and may be associated with genetic factors,hair follicular changes,bacterial infection,immunological factors,sexual hormones,smoking and obesity.Treatment includes antibiotics,retinoids,sexual hormones,tumor necrosis factor-alpha inhibitors,laser and surgery.This article presents the advances in the pathogenesis and treatment of AI,which may benefit its prevention and control.