摘要系统性红斑狼疮是一种复杂的慢性自身免疫性疾病,其多样的临床表现和复杂的实验室检查结果造成了对该病监测的困难.一个准确可靠的系统性红斑狼疮活动性评估体系是选择治疗方案及评估预后的重要依据.系统性红斑狼疮反应指数是一种新的评分系统,由医生全面评估、英岛狼疮评估组指数、系统性红斑狼疮疾病活动性指数( SELENA-SLEDAI)三部分组成,能够更好地指导临床治疗及判断患者预后,使患者维持心身健康,改善生活质量.

abstractsSystemic lupus erythematosus (SLE) is a chronic complex autoimmune disorder with various clinical manifestations and laboratory abnormalities,which have made it difficult to evaluate disease activity.A reliable and sensitive evaluation system can provide essential evidence for the selection of treatment strategies and prediction of prognosis.SLE responder index (SRI),as a new composite measurement system that consists of criteria from 3 different validated indices,including safety of estrogens in lupus erythematosus national assessment-systemic lupus erythematosus disease activity index (SELENA-SLEDAI),physician global assessment (PGA) and the British Isles Lupus Assessment Group (BILAG) 2004,can offer a better guide to the treatment and prediction of prognosis of SLE,so as to facilitate the maintenance of psychosomatic health and improvement of quality of life in patients with SLE.