摘要玫瑰痤疮是一种常见的慢性炎症性皮肤病,根据临床表现不同可分为红斑毛细血管扩张型、丘疹脓疱型、肥大型和眼型.美国国家玫瑰痤疮协会的诊疗指南认为,玫瑰痤疮应按照不同亚型给予相应的治疗.治疗方法包括一般护理、药物、激光、手术等.目前针对红斑毛细血管扩张型的α肾上腺素能受体激动剂、β受体阻滞剂、肉毒素A及针对丘疹脓疱型的亚抗生素剂量多西环素、伊维菌素等的出现,为治疗玫瑰痤疮提供了可能.由于酒石酸溴莫尼定、亚抗生素剂量多西环素、伊维菌素的使用时间较短,其安全性及功效性尚需更多的临床研究证据.

abstractsRosacea is a kind of common chronic inflammatory skin disease.According to clinical manifestations,rosacea can be divided into erythematous telangiectatic type,papulopustular type,hypertrophic type and ocular type.As the guideline of the American National Rosacea Society mentions,rosacea should be treated according to its subtypes.The treatment of rosacea mainly includes skin care,drugs,lasers,surgery,and so on.The development of new drugs,such as α-adrenergic receptor agonists,β-blockers and botulinum toxin-A targeting erythematous telangiectatic rosacea,and subantimicrobial-dose doxycycline and ivermectin targeting papulopustular rosacea,has brought possibilities to treat rosacea effectively.Owing to lack of experience in application of brimonidine tartrate,subantimicrobial-dose doxycycline and ivermectin,more evidence from clinical research is needed to evaluate their safety and efficacy.