摘要目的 研究非侵入性的空间分辨近红外光谱用于休克患者床旁监测的可行性.方法 采集25例休克患者的颈中心静脉血样并检测其中心静脉血氧饱和度(ScvO2),利用自行开发的非侵入性空间分辨近红外光谱(SR-NIRS)设备检测患者颈中心静脉附近的组织血氧饱和度(StO2).此外,利用常规方法对患者的动脉血氧饱和度(SaO2)与氧分压(PO2)进行了检测.对StO2与ScvO2、SaO2、PO2之间的相关性进行分析.结果 休克患者的StO2水平与ScvO2水平高度相关(r=0.84,P＜0.001),并且具有较高的一致性系数(0.80).结论 采用SR-NIRS设备在颈内静脉附近检测的StO2可作为休克的监测指标;非侵入的SR-NIRS监测可作为无创、持续的休克床旁监测手段.

abstractsObjective To study the feasibility of non-invasive spatially-resolved near-infrared spectroscopy (SR-NIRS) in clinical bedside monitoring of shock.Methods The central venous blood samples of 25 patients with shock were collected and the central internal jugular central vein oxygenation (ScvO2) level was measured.The self-developed non-invasive SR-NIRS device was used to measure tissue blood oxygen saturation (StO2) surrounding the region of jugular central vein.In addition,the artery oxygen saturation (SaO2) and partial pressure of oxygen (PO2) were also measured using conventional methods.The correlation between StO2 between ScvO2,SaO2 and PO2 was analyzed.Results StO2 levels in shock patients were highly correlated with ScvO2 levels (r=0.84,P＜0.001) and the concordance coefficient of 0.80 was high.Conclusion StO2 value collected from the surrounding region of jugular central vein by SR-NIRS device can be used as an indicator of shock suggesting the potential of noninvasive SR-NIRS for bedside shock monitoring.