摘要目的 对比分析肝损伤的高危因素,探讨热断层扫描成像(TTM)技术在肝损伤诊断及筛查中的应用.方法 选择3582例体检者为研究对象,收集其一般临床资料及相关理化检验指标,并对其进行TTM检查.分析TTM检查结果与一般临床资料及相关理化指标的关系.对比分析TTM检查确定为肝损伤阴性和阳性者的一般临床资料和理化指标.结果 无论从样本数值统计,还是从样本分组比较,肝损伤阳性与阴性者的肝损伤程度和主要相关指标(除体质量和低密度脂蛋白胆固醇水平)均存在差异(均P<0.05).当以氨基转移酶作为诊断标准时,TTM检查对肝损伤的诊断敏感度为93.18％,特异度为68.34％,阳性预测值为54.34％,阴性预测值为90.32％.结论 TTM检查不仅能反映肝损伤状态,而且能反映其损伤程度,是评价肝损伤的重要指标和必要补充.

abstractsObjective To compare and analyze the high risk factors of liver injury, and to explore the application of thermal texture maps (TTM) technology in the diagnosis and screening of liver injury. Methods A total of 3582 medical examiners were selected as subjects, and their general clinical data, the related physical and chemical test results and TTM results were collected. The relationship between TTM results and general clinical data and related physical and chemical results was statistically analyzed. The general clinical data and physical and chemical results of subjects with TTM negative and TTM positive liver injury were compared from the sample value statistics and the sample group comparison. Results The differences in the degree of liver damage and the main related indicators between the two groups were statistically significant (all P<0.05), except for the body mass and low-density lipoprotein cholesterol level. When using aminotransferase as the standard, the diagnostic sensitivity of TTM for liver injury was 93.18％, the specificity was 68.34％, the positive predictive value was 54.34％, and the negative predictive value was 90.32％. Conclusions TTM examination can not only reflect the state of liver injury, but also reflect the degree of injury. TTM is an important index and necessary supplement for evaluating liver injury.