摘要器官移植的成功有赖于防止急性排斥反应的发生.细胞免疫和体液免疫两种机制参与移植排斥的理论已经成为共识,其中T细胞和B细胞分别作为介导排斥反应的细胞免疫和体液免疫的主要效应成分已经被广泛研究.NK细胞的自然杀伤功能在移植中的重要性随着对其实验研究成熟可行,也逐渐成为一个感兴趣的介导排斥反应物的研究领域,使学者们更加期望借此叮以解释和降低临床急性排斥的发生率.就NK细胞表面受休(immunoglobulin-like receptors)KIR和肾脏移植的研究进展,本文进行简要综述.

abstractsThe success of organ transplantation depends on the prevetion of acute rejection. T and B lymphocytes, the major components of the cellular and humoral immunization mediating the rejection response, respectively, have been extensively studied. The importance of matural killer(NK) cells in transplantation has become an increasing area of interest as reagents for their study have become available. Basing on this on the killer immunoglobulin-like receptor in the acute rejection response with kidney transplantation.