换一批摘要胰岛移植具有创伤小、风险低、可阻止或延缓慢性并发症、有望根治糖尿病等优点,但是胰岛的分离、纯化及移植技术含量高,导致胰岛的回收率仍然较低;另外,供体短缺、移植后移植物及其功能的维持、免疫排斥反应等限制了胰岛移植在临床的广泛应用.
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abstractsClinical islet transplantation is currently being explored as a treatment for its superiorities of lesser in vasive,lower risk,avoiding or preventing chronic complications.Because of the difficulty in isolation,purification and transplantation,the yield of islet is lower than needed;shortage of donor,difficulty in obtaining adequate islet cells for sustaining B cell mass and function over time,and immune rejection reactions are the hurdels to widespread application of islet transplantation.
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医学主题词
胰岛移植(Islets of Langerhans Transplantation)糖尿病(Diabetes Mellitus)免疫(Immunity)胰岛(Islets of Langerhans)移植(Transplantation)
分类号
R6（外科学）
栏目名称
DOI
10.3760/cma.j.issn.1673-4203.2009.03.017
发布时间
2009-04-30（万方平台首次上网日期，不代表论文的发表时间）
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