摘要乳腺梭形细胞癌是一种罕见的乳腺癌亚型,具有肿瘤偏大、分期晚、组织学分级高、激素受体阴性的临床病理特点,易出现局部复发,淋巴结转移少见,血行转移常见,预后差.由于该病临床发病率较低,我们对其了解有限,如何早期发现、诊断及提高疗效是目前临床需要解决的问题.本文就梭形细胞癌的临床病理特征、诊断、治疗及预后作简要综述.

abstractsSpindle cell carcinoma of the breast (SpCC) is a very rare variant of breast cancer characterized as large tumor size,high histological grade and high negative expression of hormone receptors and HER2/neu protein.It has a high tendency for local recurrence and distant metastasis,while the axillary lymph node metastasis is less common occured,which leads to poor outcomes.Given the relatively low incidence,our knowledge about SpCC is limited.The main unsolved obstacles are the early dection and diagnosis,and the improvement in treatments.Herein,this article reviewed the clinicopathologic characteristic,diagnosis,treatment and prognosis of the spindle cell carcinoma of breast.