肠道菌群对结肠癌术后短期预后和长期预后的影响
Relationship between gut microbiota and postoperative outcomes of colorectal cancer
摘要肠道菌群在结肠癌的发生发展过程中起到重要作用,例如具核梭杆菌、消化链球菌以及嗜热链球菌等。目前结肠癌患者治疗手段以手术为主,术后辅以放化疗等方式。肠道菌群对结肠癌的影响并不仅限于肿瘤自身。当肿瘤切除后,肠道菌群仍处于紊乱状态,会影响患者的短期预后和长期预后,因此了解肠道菌群与结肠癌预后之间的关系有助于改善患者的预后,减少术后并发症的发生。本文将从肠道菌群影响结肠癌患者短期预后和长期预后作一综述。
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abstractsGut microbiota plays an important role in the development of colorectal cancer, such as Fusobacterium Nucleatum, Peptostreptococcus and Streptococcus thermophilus. At present, Surgery is the mainly treatment strategy of colorectal cancer patients, supplemented by postoperative radiotherapy and chemotherapy. The influence of gut microbiota on colorectal cancer is not limited to the tumor itself. After tumor resection, gut microbiota is still in a state of disorder, which will affect the short-term and long-term prognosis of patients. Therefore, understanding the relationship between gut microbiota and prognosis of colorectal cancer is helpful to improve the prognosis of patients and reduce postoperative complications. In this review, the author will summarize the influence of gut microbiota on short-term and long-term prognosis of colorectal cancer patients.
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