摘要黄斑前膜是伴有视力下降、视物变形等症状的玻璃体黄斑疾病.不完全玻璃体后脱离在黄斑前膜的发病机制中起着重要作用.目前治疗黄斑前膜主要有观察、药物和手术.药物玻璃体溶解术是指利用酶促使玻璃体液化,并且诱导玻璃体后脱离.玻璃体腔内注射微纤溶酶而不行玻璃体切除术,导致完全玻璃体后脱离,为药物治疗黄斑前膜提供了新的方案.但玻璃体溶解药物用于治疗黄斑前膜成功率不高,并发症时有发生.药物治疗黄斑前膜还需要更多临床研究,所以手术仍是目前主要的治疗方式.

abstractsThe epiretinal membranes is a vitreo macular disease associated with symptoms such as decreased vision and visual distortion.The vitreo-retinal interface plays a critical role in the development of epiretinal membranes.At present,the treatment of epiretinal membranes includes observed,surgery and medication.The term pharmacologic vitreolysis refers to the use of enzymes to liquefy the vitreous gel,and to induce posterior vitreous detachment.Recently,it was shown that intravitreal injection of plasmin enzyme without the performance of vitrectomy induced complete posterior vitreous detachment,which brought the dawn of the drug treatment for epiretinal membranes.However,the rate of success for drug treats epiretinal membranes is not high,complication often occur.More clinical studies are needed for the medication.So surgery is still the main treatment for epiretinal membrane.