摘要目的 通过对名老中医田从豁教授治疗退行性膝骨关节病临床经验的验证性研究,探讨适宜于名老中医经验传承验证性研究的有效方法.方法 通过名老中医数据库,利用多种数据挖掘方法,以田从豁教授治疗退行性膝骨关节病的针灸处方为中心,采用多组验证对照的临床研究设计方法,全方位进行该经验的验证性研究.结果 以田从豁教授的经验针灸处方为主的三个治疗组(田教授组,继承人组、资深医师组)治疗退行性膝骨关节病疗效相近.与基线相比较,田教授组膝关节疼痛评分下降1.20分(t=9.00,P＜0.05),继承人组下降1.13分(t=15.76,P＜0.01),资深医师组下降1.1分(t=15.99,P＜0.05),对照组下降1分(t=10.42,P＜0.05),4组在改善膝关节疼痛方面均有良好效果；田教授组,继承人组、资深医师组3组间比较(F=2.64,P＞0.05),改善膝关节疼痛评分无明显差异；与对照组比较,前三组的膝关节疼痛评分改善明显(t=3.81,P＜0.01),前三组在改善膝关节疼痛方面优于对照组.结论 经验针灸处方具有可重复性,安全、可靠、稳定.

abstractsObjective To find a method to inherit the experiences of famous senior TCM physicians,through verification and inheritance research of Professor Tian Cong-huo's clinical experience on degenerative gonarthrosis treatment.Methods By means of database of famous senior TCM physicians and various data explore methods,we performed multi-group controlled verification on Professor Tian Cong-huo's acupuncture prescription on degenerative gonarthrosis,in order to investigate the experience thoroughly.Results The three groups treated by Professor Tian Cong-huo's acupuncture prescription got similar therapeutic effects,and patients' symptoms have been relieved remarkably.Compared with the baseline,the scores of the knee joint ache in the group of Professor Tian,Successor,Senior and Control were decreased 1.20 (t=9.00,P＜0.05),1.13 (t=15.76,P＜0.01),1.1 (t=15.99,P＜0.05) and 1 (t=10.42,P＜0.05),respectively.Significant improvements of pain relieves had been achieved in all groups.No significant difference was observed among the previous three groups(F=2.64,P＞0.05),which had obvious improvement effect in comparing with the control group(t=3.81,P＜0.01).Conclusion demonstrated that the group of Professor Tian,the successor,and the senior each did better in knee pain-relief than the control group.Conclusion Confirmed by our research,this acupuncture prescription proves to be repeatable,safe,reliable and stable.Perfoming inheritance and verification research of famous and senior TCM physicians could help juniors learn and investigate their predecessors academic thoughts and connotation,proceed to the next step,inherit the precious experience through verification and combination of theory and practice.