摘要目的：评价活血补气祛痰汤治疗椎基底动脉供血不足(vertebra basilar insufficiency, VBI)性眩晕的临床疗效。方法将120例VBI性眩晕患者采用随机数字表法分为2组各60例，治疗组以活血补气祛痰汤治疗，对照组以尼莫地平注射液治疗。观察2组患者的临床疗效、治疗前后眩晕强度的变化。采用经颅多普勒检测椎基底动脉平均血流速度。结果治疗组、对照组总有效率分别为91.7%(55/60)、80.0%(48/60)，2组比较差异有统计学意义(χ2＝12.234，P＝0.01)。治疗后，2组基底动脉、左侧和右侧椎动脉的平均血流速度均提高(治疗组t值分别为2.909、4.558、5.424，对照组分别为9.831、8.388、11.191， P均＜0.01)，且治疗组较对照组平均血流速度提高更显著(t值分别为7.385、6.940、3.890，P＜0.01)。2组治疗后，眩晕强度分级均较同组治疗前降低，其中治疗组眩晕强度0级、3级的患者比例变化情况优于对照组(χ2值分别为8.298、4.547，P值分别为0.004、0.033)。结论血补气祛痰汤可改善VBI性眩晕患者椎基底动脉血液供应及眩晕强度，提高临床疗效。

abstractsObjective To investigate the therapeutic effect ofHuoxue-Buqi-Qutan decoction for vertigo due to vertebrobasilar insufficiency.Methods A total of 120 patients with vertigo due to vertebrobasilar insufficiency (VBI) were randomly divided into a treatment group and a control group, with 60 patients in each group. The treatment group was treated withHuoxue-Buqi-Qutandecoction and the control group was treated with nimodipine injection. The clinical efficacy, the change of strength before and after treatment were observed; the mean blood flow velocities of the vertebrobasilar arteries were detected with transcranial Doppler.Results After the treatment, the total effective rate was 91.7% (55/60) and 80% (48/60) in the treatment group and the control group, respectively, with significant difference (χ2=12.234,P=0.001). The mean blood flow velocities of the basilar artery, left and right basilar arteries were significantly increased in both groups (tvalues were 2.909, 4.558, 5.424, 9.831 in the treatment group, and 8.388, 11.191 in the control group, allP<0.01), the improvements of the mean blood flow velocities in the treatment group were significant better than those in the control group (tvalues were 7.385, 6.940, 3.890, allP<0.01). The vertigo grade was improved in both groups after the treatment than those before the treatment, while the proportion of grade 0 and grade 3 in the treatment group was significantly better than the control group (χ2 values were 8.298, 4.5472,P=0.004, 0.033).ConclusionHuoxue-Buqi-Qutan decoction can obviously improve the vertebrobasilar blood supply and the vertigo grade in patients with vertigo due to VBI, and then improve the clinical efficacy.