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Evading the host response:Staphylococcus"hiding"in cortical bone canalicular system causes increased bacterial burden

摘要INTRODUCTIONOver the past four decades,"limb salvage"surgery, or surgery in which bulk reconstruction is needed after a large amount of bone is removed for oncologic, infectious, or traumatic pathology, has become more commonplace than amputation. While debates have raged in the clinical communities as to whether metal1–2 or allograft bone3–5 provided a better material for reconstruction, most of the evidence provided was focused on mechanical function and durability.

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作者 Stephen D.Zoller [1] Vishal Hegde [1] Zachary D.C.Burke [1] Howard Y.Park [1] Chad R.Ishmael [1] Gideon W.Blumstein [1] William Sheppard [1] Christopher Hamad [1] Amanda H.Loftin [1] Daniel O.Johansen [1] Ryan A.Smith [2] Marina M.Sprague [3] Kellyn R.Hori [4] Samuel J.Clarkson [2] Rachel Borthwell [2] Scott I.Simon [5] Jeff F.Miller [6] Scott D.Nelson [7] Nicholas M.Bernthal [1] 学术成果认领
作者单位 Department of Orthopedic Surgery,University of California,Los Angeles,1250 16th St Suite 2100,Santa Monica,CA 90404,USA [1] David Geffen School of Medicine,University of California,Los Angeles,10833 Le Conte Ave,Los Angeles,CA 90095,USA [2] Department of Internal Medicine,University of California,Los Angeles,757 Westwood Plaza,Suite 7501,Los Angeles,CA 90095,USA [3] Department of Orthopedic Surgery,University of California,Los Angeles,1250 16th St Suite 2100,Santa Monica,CA 90404,USA;David Geffen School of Medicine,University of California,Los Angeles,10833 Le Conte Ave,Los Angeles,CA 90095,USA [4] Department of Biomedical Engineering,University of California,Davis,Davis,CA 95616,USA [5] California Nano Systems Institute,University of California,Los Angeles,570 Westwood Plaza,Los Angeles,CA 90095,USA;Department of Microbiology,Immunology,and Molecular Genetics,David Geffen School of Medicine,University of California,Los Angeles 90095,USA [6] Department of Pathology,University of California,Los Angeles,1250 16th St Suite 3450,Santa Monica,CA 90404,USA [7]
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发布时间 2021-03-16(万方平台首次上网日期,不代表论文的发表时间)
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骨研究(英文版)

骨研究(英文版)

2020年8卷4期

447-457页

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