摘要INTRODUCTIONTumors, severe infection, osteoporosis, osteonecrosis, and some congenital malformations can cause large bone defects, which remain challenging in clinical practice.1 Bone defects induced by various causes are currently one of the principal causes of morbidity and disability, which decrease quality of life and endanger lives.
作者单位Department of Oral&Cranio-Maxillofacial Surgery,Shanghai Ninth People's Hospital,College of Stomatology,Shanghai Jiao Tong University School of Medicine,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology,Shanghai 200011,China[1]State Key Laboratory of Oral Diseases,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China[2]