摘要Objective: To evaluate the impact of salinity changes in the rearing environment on the haemocyte activities of pearl oyster Pinctada martensii (P. martensii). <br> Methods:Three salinity treatments including 12‰, 22‰, and 32‰were tested. Haemocyte mortality rate and neutral red retention (NRR) assay were used to investigate the impact of rearing salinity on the haemocyte activities of pearl oyster. <br> Results:Results from the present study indicated that salinity significantly affected the haemocyte mortality rate of P. martensii. The highest haemocytes mortality rate was observed in the 12‰treatment, and the lowest mortality rate was observed in the 32‰treatment. NRR time was also significantly affected by the salinity. The highest NRR time was observed in the 32‰treatment, and the lowest NRR time was observed in the 12‰treatment. <br> Conclusions:Results from the present study indicated that salinity<22‰had significant impact on the haemocyte mortality rate and NRR time. Reducing the environmental salinity will pose an additional stress and may also reduce the defense capacities of P. martensii and make them more susceptible to parasites and bacteria.