高效毛细管电泳-单链构象多态性分析K-ras基因突变
SSCP of K-ras gene mutations by high performance capillary electrophoresis
摘要篇首: Lung cancer is one of the most prevalent cancers and the leading cause of cancer mortality in the world. It is of great importance to study mutation of gene related to lung cancer. Mutations in cellular ras gene have been strongly implicated in various stages of mammalian tumorigenesis. In human tumors, the point mutations which have been identified have largely been localized to codon 12,13 or 61 of three ras genes : H-ras, K-ras and N-ras.
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