摘要Objective: Given the importance of having knowledge on the hemovigilance process in nursing care, the present study was conducted to investigate the effect of the hemovigilance education on nursing students' knowledge using a conceptual map. The current research was a semi-experimental study. Methods: The samples consisted of 60 nursing students who were selected based on the inclusion criteria using the census sampling method. Thereafter, these participants were randomly assigned into the two groups: experimental and control groups. The required data were collected before, immediately after, and 1 month after the education using the hemovigilance knowledge questionnaire. Accordingly, the validity of this questionnaire was confirmed, and its reliability using the Cronbach's alpha coefficient was reported as 0.83. The education process was conducted during a 4-week period. Thereafter, the collected data were analyzed using descriptive and inferential statistics by SPSS v25. Results: The results reveal that a significant difference existed between the knowledge scores of students in the experimental group compared with that of the control group during different times (including before, immediately after, and 1 month after the education) (P < 0.0001). Of note, hemovigilance education had a significant effect on the students' knowledge (P < 0.0001). Conclusions: Due to the effect of the hemovigilance education on the students' knowledge and by applying the conceptual map in the easy transfer of the educational concepts, it is recommended that the results of the present study be used to strengthen the theoretical and clinical education of nursing students.