摘要The prevention and treatment of myocardial ischemia is a hot and difficult point in clinical research and animal experimental research in the cardiovascular field.The combined disease and syndrome animal model with the disease characteristics of Western medicine and guided by the theory of Chinese medicineto replicate the "syndrome" of Chinese medicine on the model animals by using experimental methods is an effective tool for the research of Chinese medicine. This article summarized the methoding methods and evaluation index of the animal model combined disease of coronary heart disease myocardial ischemia with cold blood stasis, phlegm and blood stasis, qi deficiency and blood stasis syndrome, kidney deficiency and blood stasis, and concluded the treatment of Traditional Chinese medicine. At the same time, it analyzed the main deficiencies of myocardial ischemia syndrome combined with animal models to provide reference for the establishment and research of related animal models.