摘要Objective: To evaluate the efficacy of Qing Gan Huo Xue Prescription(QGHXP)in the treatment of patients with alcoholic liver cirrhosis(ALC)of damp and heat stasis syndrome. Methods: A total of 69 patients with ALC were randomly divided into TCM group(n=35) and control group(n=34). The TCM group was given QGHXP 1 pack TID orally. Control group received polyene phosphatidylcholine capsule 456 mg TID for 24 weeks. The observation measurements are symptom efficacy rate,serum level of liver enzyme,and non-invasive liver cirrhosis evaluation,including liver stiffness measurement(LSM)examininged by FibroTouch,APRI score,FIB-4 index and Maddrey discriminant function. Results: The symptom efficacy rate of the experimental group and the control group was 85.70％ and 61.80％(P=0.024). Liver enzyme levels(serum ALP,γ-GT, AST and ALT)of TCM group were lower than those of control group(P<0.05). LSM of TCM group was reduced after treatment,and was significant lower than control group(14.19±1.49)vs.(15.06±1.24)(P<0.05). The APRI scores,FIB-4 index and Maddrey discriminant functions of TCM group were lower than those of control group(P<0.05). Conclusion: QGHXP is an effective alternative for the treatment of damp and heat stasis syndrome of ALC in improving liver function and clinical symptoms.