摘要The corona virus disease 2019 (COVID-19) is an acute respiratory infection caused by the binding of SEVERE acute respiratory syndrome coronavirus 2 (SARS-COV-2) and the angiotensin-converting enzyme 2 (ACE2) receptor to the host target organ. New research suggests that COVID-19 may be a systemic infectious disease and a systemic inflammatory disease.Symptoms and signs of the digestive system are often found in patients with coVID-19 following acute infection.At present, despite the existence of some coronavirus-related digestive diseases (such as gastrointestinal diseases, liver injury, pancreatic injury, etc.), the pathogenesis of COVID-19 with digestive symptoms in existing studies is still unclear, and relevant guidelines and expert consensus are not enough for clinical diagnosis and treatment. Therefore, it is extremely important to understand the clinical manifestations, pathogenesis and prognosis of coVID-19 patients with digestive system.