The Frank-Starling mechanism is not enough:blood volume expansion prominently decreases pulmonary O2 uptake
摘要Dear Editor,To date,the uncertainty remains whether the circulatory system of women and men can accommodate additional blood volume(BV)to enhance cardiac capacity[peak cardiac output(Qpeak)]and aerobic capacity[peak O2 uptake(VO2peak)][1-4].In the general population,BV is typically below the optimal levels achieved through endurance training,suggesting that expanding BV may have clinical benefits[5].
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