摘要Objective: To investigate the early detection of the damage of cochlear activity by using distortion product otoacustic emissions (DPOAE) (DP-gram) comparing to the results of the impedance audiometry. <br> Methods: We examined 53 patients including 43 hemodialyzed patients, and 10 controls. First it was applied a tympanometry, and then in normal results we applied impedance audiometry and DPOAE (DP-gram). <br> Results: We found sensorineural hearing loss in 67% of audiometric results of the hemodialyzed patients and there was a decrease of the DPOAE amplitude in 77% of hemodialyzed patients. In the control group there was one patient (10%) with neurosensorial in high frequencies hearing loss in both measurements with audiometry and DPOAE. <br> Conclusions: There is a sensorineural hearing loss observed in most of the patients with chronic renal failure. DPOAE audiogram shows lower amplitudes than impedance audiometry and it can be used for the early detection of cochlear damage.