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Efficacy of Willis covered stent of intracranial pseudoaneurysms in the internal carotid artery:A systematic review and meta-analysis

摘要Objective: To evaluate the efficacy of a novel coated stent in thetreatment of intracranial pseudoaneurysm.Methods: MEDLINE, EMBASE, and PubMed databases weresearched for literature published between 1990 and April 2022according to PRISMA guidelines. All studies with ≥10 patientsreporting successful implantation of Willis covered stent, therapeuticeffect, complications, and postoperative follow-up were included.The combined incidence and corresponding 95% confidenceintervals were assessed using a generalized linear mixed method andrandom effects model.Results: Five studies (116 patients with pseudoaneurysms) wereincluded. The experimental groups in the selected studies showeda combined technical success rate of 81.03% (OR=18.31,95%CI=9.39-35.69, I2=79%, P<0.001). Clinical follow-up showed thatthe complete cure rate was as high as 94.4% after the follow-up(OR=106.81, 95% CI=39.08-291.88, I2=0%, P=0.71).Conclusions: Willis covered stent is feasible, safe, and effective inthe treatment of intracranial pseudoaneurysm.

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作者 Li Lin [1] Shao-Wei Xiang [2] Yan-Ling Sun [3] Yuan Chen [4] Zhe Wu [3] Zhi-Feng Ning [5] Ding-Wen Shen [6] Xue-Qin Sima [3] Qi-Qiang Wen [2] Gui-Lai Wei [7] Qing-Yong He [8] 学术成果认领
作者单位 Department of Biochemistry,Basic School School,Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [1] The Third Surgery Department,Enshi State Central Hospital,Enshi State,Hubei Province 445000,China [2] Department of Histology and Embryology,Basic School School,Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [3] Department of Cardiothoracic Surgery,Xianning Central Hospital,Hubei University of Science and Technology,Xianning City,Hubei provinceProvince 437100,China [4] Department of Human Anatomy,Basic School School,Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [5] Department of Parasite,Basic School School,Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [6] Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [7] School of Physical Education,Hubei University of Science and Technology,Xianning City,Hubei Province 437100,China [8]
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DOI 10.4103/2221-6189.388031
发布时间 2023-11-06
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