换一批摘要With the development of genome sequencing for many organisms, more and more raw sequences need to be annotated. Gene prediction by computational methods for finding the location of protein coding regions is one of the essential issues in bioinformatics. Two classes of methods are generally adopted: similarity based searches and ab initio prediction. Here, we review the development of gene prediction methods, summarize the measures for evaluating predictor quality, highlight open problems in this area, and discuss future research directions.
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分类号
Q81（生物工程学《生物技术》）
发布时间
2006-07-31（万方平台首次上网日期，不代表论文的发表时间）
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