摘要Electroencephalography-correlated functional magnetic resonance imaging (EEG/fMRI) can be used to identify blood oxygen level-dependent (BOLD) signal changes associated with both physiological and pathological EEG events. Here, we implemented continuous and simultaneous EEG/fMRI to identify BOLD signal changes related to P3b component of P300, and 64 channels of EEG were recorded in 11 subjects during Landot Ring task inside a 1.5 T functional magnet resonance (MR) scanner using an MR-compatible EEG recording system. Functional scanning by echoplanar imaging covered almost the entire cerebrum every 2 s, leaving gaps of 2 s without scanning. Off-line MRI artifact subtraction software was applied to obtain continuous EEG data. Additionally, a P300 wave matched filter was constructed to inspect P300 wave occurrence following every target stimulus, target stimuli inspected to induce P300 were detected and their MRI scan number were then used as input for an event-related fMRI analysis. Finally MRI statistical parametric maps were constructed and corrected for multiple comparisons. By random effect group analysis, activations were detected in the right superior parietal lobule and bilaterally in inferior parietal lobule(p<0.001, uncorrected). The results demonstrated the upper regions were sources of P3b component and involved in target detection in memory comparison task.