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Comparison of the early curative effect in patients undergoing mechanical vs.bioprosthetic aortic valve replacement with concomitant annuloplasty by the Nicks procedure

摘要Background The probability of prosthesis-patient mismatch(PPM)is high in aortic valve replacement surgery for small aortic valve annulus,which increases the postoperative prosthetic valve transvalvular pressure gradient.Concurrent aortic annuloplasty is a commonly applied surgical procedure,but there is currently no uniform stan-dard or guideline on the type of prosthetic valve that should be used during surgery.Therefore,this study aimed to analyze whether there was any difference in the short-term prognosis between the choice of mechanical valves and bioprosthetic valves during aortic valve replacement surgery with concomitant aortic annuloplasty by the Nicks pro-cedure.Methods A retrospective analysis was conducted based on the clinical data from 55 patients undergoing aortic valve replacement surgery with concomitant annuloplasty by the Nicks procedure at the Cardiac Surgery De-partment of Guangdong Provincial People's Hospital from November 2021 to December 2023.In this study,all pa-tients received aortic annuloplasty by the Nicks procedure.Among these patients,30 were in the mechanical valve group,while the other 25 were in the bioprosthetic valve group.Data including left ventricular end-diastolic/end-systolic diameters,left ventricular ejection fraction,interventricular septal thickness,left ventricular posterior wall thickness,transvalvular pressure gradient,left ventricular fractional shortening,and left ventricular mass index were collected 1 week preoperatively and 1 week and 3 months postoperatively.Information on gender,age,body surface area,types of perioperative complications,operation time,complication rates,and outcomes was also col-lected.Results Among the 55 patients enrolled in this study,4 died.The main causes of death included postopera-tive low cardiac output syndrome,severe pulmonary infection,and multi-organ dysfunction.Meanwhile,there was a statistically significant difference in left ventricular end-diastolic diameter between the mechanical valve group and the biological valve group 1 week after surgery.However,differences in other indicators such as aortic cross-clamp duration,cardiopulmonary bypass duration,postoperative ventilator support duration,postoperative inten-sive care unit(ICU)stay,total postoperative hospital stay,and echocardiography results 1 week and 3 months post-operatively were not significant between the two groups.Conclusions For patients undergoing aortic annuloplas-ty by the Nicks procedure in the aortic valve replacement surgery,the postoperative recovery time is not significant-ly different between the bioprosthetic and mechanical valve groups.Additionally,there is no notable difference in the improvement of left ventricular function or the reduction of PPM incidence between the two types of valves.[S Chin J Cardiol 2024;25(1):29-37]

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岭南心血管病杂志(英文版)

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