摘要Background The age,creatinine levels,and the ejection fraction Ⅱ score(ACEF Ⅱ score)are significant indi-cators for assessing inflammation and predicting adverse outcomes following cardiac surgery.Our objective was to investigate the predictive value of the recently updated ACEF Ⅱ score concerning perioprative blood transfusion in adult patients undergoing cardiac surgery.Methods A retrospective review was conducted involving adults(≥ 18 years)who underwent cardiac surgery for heart disease between January 2019 and June 2019.The primary outcome measure was perioperative blood transfusion among adult patients.Multivariable logistic regression and receiver operation characteristic(ROC)analysis were applied to analyze the link between the ACEF Ⅱ score and periopera-tive blood transfusion.Results A total of 415 patients were included,participants were stratified into three groups based on their ACEF Ⅱ scores level:ACEF Ⅱ＜0.666,0.666 ≤ ACEF Ⅱ＜0.950,and 0.950 ≤ ACEF Ⅱ ≤4.781.Multi-variable Logistic regression analysis indicated that a high ACEF Ⅱ score(OR:3.59,95％CI:1.68-7.67,P＜0.001)was independently associated with an increased risk of perioperative blood transfusion among adults undergoing cardiac surgery.Furthermore,the area under the receiver operating characteristic curve for predicting perioperative blood transfusion risk using the ACEF Ⅱ score was found to be 0.607.The Pearson correlation coefficient showed a direct and statistically significant positive correlation between ACEF Ⅱ score and perioperative blood transfusion(r=0.17,P＜0.001).Conclusions In conclusion,our findings suggested that the ACEF Ⅱ score possessed signifi-cant predictive value regarding related to perioperative blood transfusions during cardiac surgical procedures in adult patients.The higher the ACEF Ⅱ score,the higher incidence of perioperative blood transfusions.[S Chin J Cardiol 2024;25(4):207-215]