摘要1 Risk of stroke in patients with high CHA2DS2VASc and no documented arrhythmiasRecent studies have suggested that patients with high CHA2DS2VASc-score [Congestive Heart failure,hypertension,Age ≥ 75 years (doubled),Diabetes,Stroke (doubled),Vascular disease,Age 65-74 years,Sex category (female sex)] thromboembolic complications occurred irrespective of the presence of atrial fibrillation (AF) and anticoagulant therapy may be initiated irrespective of documented AF.[1,2] In fact,Tischer,et al.,[1] found that up to a score of 6,the prevalence of stroke was higher in patients with AF.However,beyond a score of 6,the prevalence of stroke was high irrespective of AF.Other authors have suggested that the risk of stroke is particularly high in the presence of arrhythmic symptoms,[2] previous myocardial infarction,[3] or heart failure[4] therapy in patients with high CHA2DS2VASc-score,even in the absence of documented arrhythrnias.