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Berg Balance Scale score is a valuable predictor of all-cause mortality among acute decompensated heart failure patients

摘要OBJECTIVE To investigate possible associations between physical function assessment scales,such as Short Physical Performan-ce Battery(SPPB)and Berg Balance Scale(BBS),with all-cause mortality in acute decompensated heart failure(ADHF)patients.METHODS A total of 108 ADHF patients were analyzed from October 2020 to October 2022,and followed up to May 2023.The asso-ciation between baseline clinical characteristics and all-cause mortality was analyzed by univariate Cox regression analysis,while for SPPB and BBS,univariate Cox regression analysis was followed by receiver operating characteristic curves,in which the area under the curve represented their predictive accuracy for all-cause mortality.Incremental predictive values for both physical function as-sessments were measured by calculating net reclassification index and integrated discrimination improvement scores.Optimal cut-off value for BBS was then identified using restricted cubic spline plots,and survival differences below and above that cut-off were compared using Kaplan-Meier survival curves and the log-rank test.The clinical utility of BBS was measured using decision cur-ve analysis.RESULTS For baseline characteristics,age,female,blood urea nitrogen,as well as statins,angiotensin-converting enzyme inh-ibitors,angiotensin Ⅱ receptor blockers,or angiotensin receptor-neprilysin inhibitors,were predictive for all-cause mortality for ADHF patients.With respect to SPPB and BBS,higher scores were associated with lower all-cause mortality rates for both assessments;si-milar area under the curves were measured for both(0.774 for SPPB and 0.776 for BBS).Furthermore,BBS ≤ 36.5 was associated with significantly higher mortality,which was still applicable even adjusting for confounding factors;BBS was also found to have great cli-nical utility under decision curve analysis.CONCLUSIONS BBS or SPPB could be used as tools to assess physical function in ageing ADHF patients,as well as prognostica-te on all-cause mortality.Moreover,prioritizing the improvement of balance capabilities of ADHF patients in cardiac rehabilitation regimens could aid in lowering mortality risk.

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