摘要Cardiac amyloidosis (CA) is characterized by the deposition of the misfolded amyloid precursor proteins in the myocardium of the heart. The systemic form of CA is mainly caused by either the mis-folded monoclonal immunoglobulin light chains (kappa and lambda) or transthyretin.[1]The clinical manifestations are mainly overlap with symptoms of other cardiovascul-ar diseases mostly hypertrophic cardiomyopathy and he-art failure. Some cases often overlooked and remains un-diagnosed because of the atypical clinical manifestations,especially in the elderly. The incidence of CA has incre-ased across the world recently.[2]This paper reports the di-agnosis and treatment of an elderly male patient with wi-ld-type transthyretin CA (ATTRwt-CA). Combined with the standardized diagnosis procedure of CA,it can impr-ove the understanding and diagnosis of CA among cardi-ovascular physicians.