摘要目的 对照评估三维超声VOCAL(virtual organ computer-aided analysis)技术与二维超声测量甲状腺体积的一致性和重复性.方法 采用二维超声和三维超声测量50例18～68岁女性成人的甲状腺体积.二维超声测量甲状腺最大切面的3个径线(L、H、W),用经典的椭圆体公式V=0.523×L×H×W计算甲状腺体积;三维超声VOCAL技术先获取甲状腺三维数据,而后用VOCAL技术测量甲状腺体积;最终对比分析两种测量方法 .结果 三维超声VOCAL技术与传统二维超声测量甲状腺体积,操作者组内的变异系数分别为0.738％、1.59％,95％一致性界限分别为(-0.26 cm3,0.22 cm3)、(-0.32 cm3,0.46 cm3);组间相关系数分别为0.970xx、0.942xx,95％一致性界限分别为(-0.36 cm3,0.37 cm3)、(-0.75 cm3,0.64 cm3).三维超声VOCAL技术测量甲状腺体积组内变异系数小、组间相关系数高、95％一致性界限宽度窄,说明三维超声VOCAL技术测量甲状腺体积的重复性优于传统二维超声.结论 三维超声VOCAL技术测量甲状腺体积的重复性高,优于传统二维超声,其作为一种安全、简单、易行、精确的测量方法,为临床测量不规则脏器体积提供可靠、有效的新方法.

abstractsObjective To evaluate and compare the consistency and repeatability of three-dimensional ultrasound (3D-US) virtual organ computer-aided analysis (VOCAL) technique and two-dimensional ultrasound (2D-US) in the measurement of thyroid volume.Methods The thyroid volume of 50 healthy female adults aged 18 to 68 years were measured by 2D-US and 3D-US.The 2D-US was used to measure the three diameter lines (L,H,W) of the largest thyroid section,and the thyroid volume was calculated by the classical ellipsoid formula V=0.523×L×H×W.The 3D-US VOCAL technique was used to acquire the thyroid three-dimensional data,and VOCAL software was used to measure the thyroid volume.The two methods of measurement were also compared and analyzed.Results The coefficient of variation in the intra-assay was 0.738％ and 1.59％ respectively for the 3D-US VOCAL technology and traditional 2D-US measurement of thyroid volume,and the 95％ limit of agreement in the intra-assay was (-0.26 cm3,0.22 cm3) and (-0.32 cm3,0.46 cm3).In addition,the correlation coefficient in the inter-assay were 0.970xx and 0.942xx,and the 95％ limit of agreement were (-0.36 cm3,0.37 cm3) and (-0.75 cm3,0.64 cm3).To compare the two methods of measuring thyroid volume,the 3D-US VOCAL had a lower variation coefficient in the intra-assay,a higher correlation coefficient in the inter-assay and a narrower 95％ limit of agreement,which showed that the repeatability of the 3D-US VOCAL technique measuring was better than the traditional 2D-US in measuring thyroid volume.Conclusions The 3D-US VOCAL technique shows a higher repeatability in measuring thyroid than traditional 2D-US.As a safe,simple and feasible precise measurement method,it provides a reliable and effective new method for clinical measurement of irregular organ volume.