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Advances in Photoacoustic Imaging for Interventional Application

摘要The incidence and mortality of cardiovascular diseases and gastrointestinal cancer have gradually increased in recent years, and these diseases have become major social and public-health concerns.New requirements have been proposed for the clinical diagnosis of these diseases in the hope that, by accessing accurate structural information, to further grasp the functional information which closely related to the development of the diseases.Photoacoustic imaging is a new imaging method in which ultrasonic signals are generated from biological samples by laser-pulse irradiation.It has the advantages of high optical contrast, large ultrasound penetration depth, and high resolution.Additionally, it can acquire spectral information.The integration of a photoacoustic imaging system into a tiny imaging catheter can realize interventional imaging based on photoacoustic principles.The combination of structural imaging of cardiovascular and gastrointestinal lesion regions with photoacoustic spectroscopy to identify and quantify tissue components can realize highly sensitive functional imaging.After surveying the recent progress in the development of the photoacoustic imaging method for interventional application, with a particular emphasis on intravascular photoacoustic imaging, photoacoustic endoscopy, and photoacoustic spectroscopy, we summarize and identify future research directions for interventional photoacoustic imaging.

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作者单位 School of Mechanical and Electric Engineering, Guangzhou University,Guangzhou 510006,P.R.China [1] State Key Laboratory of Mechanics and Control of Mechanical Structures, Nanjing University of Aeronautics and Astronautics,Nanjing 210016,P.R.China;Research Lab for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,Shenzhen 518055,P.R.China [2] School of Mechanical and Electric Engineering, Guangzhou University,Guangzhou 510006,P.R.China;Research Lab for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,Shenzhen 518055,P.R.China [3] Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,P.R.China [4] Research Lab for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences,Shenzhen 518055,P.R.China [5]
分类号 TH776R331
发布时间 2019-05-31
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