摘要This study aimed to analyze the hemodynamic effects of bifurcated vessels using different blood viscosity models.Three-dimensional models of bifurcated vessels in the popliteal artery were constructed based on CT images,and hemodynamic parameters of the Newtonian,Casson,and two-phase models were calculated by the computational fluid dynamics method.Blood flowed through the popliteal artery.Blood flow velocity changed after the bifurcated vessel,with accelerated blood flow velocity in the anterior tibial artery.A low-velocity vortex region with a region of low wall shear stress(WSS)was generated outside the bifurcated vessel.Local non-Newtonian importance factors of great than 1(i.e.,IL＞1)occurred during the cardiac cycle,and IL＞1.75 occurred at the beginning and end of the cycle.Compared with the Casson and two-phase models,the Newtonian model has a larger vortex region and lower WSS.Low-velocity vortex regions and low WSS regions in the bifurcated vessels may contribute to the development of atherosclerosis.Blood exhibited non-Newtonian fluid properties in bifurcated vessels(IL＞1),and the effect of non-Newtonian properties was more pronounced at the beginning and end of heartbeats(IL＞1.75).The Newtonian model predicts a higher risk of atherosclerosis formation and the effect of non-Newtonian properties of blood should be considered in hemodynamic studies.