换一批
换一批Activation of neurogenesis in the hippocampus is a novel therapeutic target for Alzheimer's disease
Activation of neurogenesis in the hippocampus is a novel therapeutic target for Alzheimer's disease
摘要Highlights:Targeting single mechanisms of physiological (aging) and pathological (neurodegeneration) loss of function in the brain may not be sufficient.Cell–cell interactions between transplanted adult stem cells and resident cells via gap junctions have the potential to support the aging or diseased brain.These cell–cell interactions can also increase hippocampal neurogenesis.This may be a novel therapeutic strategy for Alzheimer's disease and other neurodegenerative diseases that could be applied alongside any established treatments.
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关键词
Alzheimer's diseasecell-cell interactioncell therapygap junctionsneurodegenerative diseaseneurogenesisAlzheimer's diseasecell-cell interactioncell therapygap junctionsneurodegenerative diseaseneurogenesis
栏目名称
Research Highlights
DOI
10.1002/nep3.25
发布时间
2025-02-25
基金项目
Suzuken Memorial Foundation (Japan)
Academy of Medical Sciences (United Kingdom)
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