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A case report of brain abscess caused by Nocardia cyriacigeorgica identified by metagenomic next-generation sequencing

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摘要Nocardia is an aerobic,gram-positive,and opportunistic bacillus widely distributed in the environment. Nocardia cyriacigeorgica (N. cyriacigeorgica) was first isolated in 2001 from a chronic bronchitis patient,[1]and has since been reported as an emerging clinically relevant pathogen worldwide. The diagnosis of nocardial infections remains challenging due to nonspecific symptoms and low culture sensitivity,resulting in high mortality.[2]Herein,we report a case of N. cyriacigeorgica brain abscess in an immunosuppressed patient who was successfully treated with antibiotics and surgery.

作者 Wenqing Tu ^[1] Peiting Zeng ^[2] Zhuangtian Wu ^[3] Zuyong Li ^[4] Tao Yu ^[4] Wenxian Zhang ^[3] Ran Chen ^[5] Lian Liang ^[6] 学术成果认领

作者单位 Department of Cardiology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China ^[1] Department of Hematology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China ^[2] Department of Emergency Medicine,Shenshan Medical Center,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Shanwei 516600,China ^[3] Department of Emergency Medicine,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China ^[4] Department of Clinical Laboratory,Guangzhou Eighth People's Hospital,Guangzhou Medical University,Guangzhou 510440,China ^[5] Department of Emergency Medicine,Shenshan Medical Center,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Shanwei 516600,China;Department of Emergency Medicine,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China ^[6]

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Case Letters

DOI 10.5847/wjem.j.1920-8642.2026.019

发布时间 2026-03-31（万方平台首次上网日期，不代表论文的发表时间）

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