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Management of urachal anomalies in children:insights from a retrospective cohort study

摘要Introduction While large and symptomatic urachal anomalies(UAs)often lead to surgical excision,urachal malignancy is rare,rendering prophylactic excision unwarranted.We hypothesize that in the pediatric population,the presentation of an infected UA is the predominant etiology leading to surgical intervention.Methods We retrospectively identified patients with UA from July 2012 to December 2021 evaluated in our urology outpatient.Inclusion criteria included patients ≤18 years old and confirmation of UA on ultrasound(US).Exclusion criteria were patients diagnosed with clinical mimickers on US,excision by general pediatric surgery service,or excision done concomitantly as part of another urological procedure.Results We identified a total of 78 patients with UA.Of those,35(44.9%)underwent excision.The observation cohort was younger(5 months vs.73 months,p=0.002),more likely to be asymptomatic(65.1%vs.85.7%,p=0.038),and more likely to have UA characterized as a'remnant'on US(72.1%vs.48.6%,p=0.034).Univariate analysis showed that infected or symptomatic UA,or those characterized as hyperemic,cystic,or as a diverticulum on US were more likely to be excised.Multivariable analysis shows that patients with a 'urachal cyst' classification(p=0.008)and infectious presentation(p=0.046)were more likely to undergo surgical intervention.Excision was accomplished laparoscopically(80.0%)or robotically(11.4%).No excised UA was suspicious for malignancy.Conclusion We present a large pediatric cohort with UA and found that infectious symptoms at presentation and those classified as 'urachal cyst' based on US were more likely to prompt surgical excision as compared with other factors.

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作者 Suhaib Abdulfattah [1] Iqra Nadeem [1] Yashaswi Parikh [1] Sami Shaikh [1] Sonam Saxena [1] Aznive Aghababian [1] Katherine Fischer [1] Sameer Mittal [1] Arun K Srinivasan [1] Aseem R Shukla [1] 学术成果认领
作者单位 The Children's Hospital of Philadelphia,Philadelphia,Pennsylvania,USA [1]
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DOI 10.1136/wjps-2024-000977
发布时间 2025-08-04(万方平台首次上网日期,不代表论文的发表时间)
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世界小儿外科杂志(英文)

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