摘要Objective:To explore the clinical application rules of Láogōng(劳宫PC8)by analyzing the comparison and contrast of the practice with this acupoint in ancient times and in present.Methods:Relevant literature before October 1,1949 was selected from Chinese Medical Code(Fifth Edition)and Compilation of Modern Chinese Medicine Journals and literature published after October 1,1949 was screened from China National knowledge Infrastructure(CNIK),Wanfang Data Knowledge Service Plat-form(Wanfang),VIP Chinese Journal Service Platform(VIP),Chinese BioMedine Database(CBM),Pubmed Database,and Web of Science.After screening,SQL Server database was established.The complex net-work analysis was conducted by using Gephi and the cluster analysis was performed by SPSS Statistics.Results:Before October 1,1949,Láogōng(劳宫PC8),on a single use or with a match of Dàlíng(大陵PC7),Guānyuán(关元CV4),and Zúsānlǐ(足三里ST36),was mainly used for treating ozostomia and edema due to pregnancy.However,Láogong(劳宫PC8),on a single use or with a match of Yǒngquán(涌泉KI1),Hegu(合谷LI4)and Nèiguān(内关PC6)was commonly for the treatment of toothache and the sequelae after wind stroke after October 1st,1949.Conclusion:Láogōng(劳宫PC8)is mainly used to treat local disorders or diseases pertaining to the peri-cardium meridian.The single-point therapy was commonly applied before October 1st,1949,while a combination of other points is more common afterwards and the scope of indication expands,with its application for psychiatry disorders,pain diseases and emergent diseases.Acupoints on the same merid-ian of Láogōng(劳宫PC8),ying-spring points,the back-shu points and combination between and the up-per and the lower are dominated in the selection of supplementary points.The supplementary acupoints with the highest frequency of use were specific acupoints,including five-shu points,yuan-source points,front-mu points,etc.