换一批Resveratrol and its derivates improve infl ammatory bowel disease by targeting gut microbiota and infl ammatory signaling pathways
摘要Inflammatory bowel disease (IBD) is a chronic inflammatory lesion of the intestine, mainly manifested by infiltration of intestinal inflammatory cells and imbalance of gut microbiota. Conventional treatments for IBD include antibiotics, immunosuppressive agents, 5-aminosalicylic acid, steroids and surgery, which have high toxic side effects. Resveratrol is a natural polyphenol, and its various derivatives have anti-oxidation and anti-inflammatory properties. In this paper, we comprehensively review the mechanism of resveratrol and its derivates to alleviate IBD by improving intestinal barrier, regulating the unbalanced gut microbiota, and targeting various inflammatory signaling pathways.
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ResveratrolInflammatory bowel diseaseIntestinal barrierGut microbiotaInflammatory signaling pathways
发布时间
2022-12-12（万方平台首次上网日期，不代表论文的发表时间）
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