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Baroreflex sensitivity and its implication in neurally mediated syncope in children

摘要Neurally mediated syncope(NMS)refers to an entity of syncopal disorders that can be triggered by a psychological stimulus,standing for a long time,sudden position change from supine to upright,or a muggy environment.Vasovagal syncope(VVS),also known as acute orthostatic intolerance(OI),is the main form of NMS[1]and seriously affects the quality of life of children.However,the pathogenesis of NMS has not yet been fully clarified.The mechanisms underlying NMS are considered to involve autonomic regu-lation abnormalities,low blood volume,abnormal vascular function,etc.Baroreflex sensitivity(BRS)is the sensitivity of baroreceptor reflex regulation,which controls cardio-vascular autonomic function.Abnormal regulation of the baroreflex has been identified as a fundamental mechanism underlying NMS.Arterial BRS describes the effectiveness of baroreflex during an alteration in blood pressure(BP)and is determined by evaluating changes in heart rate(HR)in response to BP alterations.

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作者 Ya-Xi Cui [1] Jun-Bao Du [2] Hong-Fang Jin [1] 学术成果认领
作者单位 Department of Pediatrics,Peking University First Hospital,Beijing 100034,China [1] Department of Pediatrics,Peking University First Hospital,Beijing 100034,China;Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education,Beijing 100191,China [2]
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DOI 10.1007/s12519-023-00693-y
发布时间 2023-12-22(万方平台首次上网日期,不代表论文的发表时间)
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世界儿科杂志(英文版)

世界儿科杂志(英文版)

2023年19卷11期

1023-1029页

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