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Does midline head positioning decrease intraventricular hemorrhage or is it futile?Without a definitive trial,we will never know

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学术成果认领

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摘要Among the 135 million births in 2020,0.6 million were extremely preterm(＜28 weeks' gestation),and 1.4 million were very preterm(between 28 and＜32 weeks' gestation)[1].Intraventricular hemorrhage(IVH)remains a major concern for these infants,particularly those＜29 weeks' gestation[2].Midline head positioning(MHP)is a widely adopted intervention in care bundles for IVH prevention in preterm infants.However,high-quality evidence supporting the efficacy and effectiveness of MHP for IVH prevention is lacking.Here,we summarize the issues with the existing evidence on MHP,including its widespread adoption in care bundles on the basis of poor quality of evidence,and high-light the urgent need for a definitive trial to determine the causal role,if any,of MHP in IVH prevention.

作者 Traci-Anne Goyen ^[1] Pranav R.Jani ^[2] Hannah Skelton ^[3] Kylie Pussell ^[4] Brett Manley ^[5] William Tarnow-Mordi ^[6] Positioning the preterm Infant for Neuroprotection(PIN)trial Investigator Collaborative Group 学术成果认领

作者单位 Department of Neonatology,Westmead Hospital,Westmead,NSW,Australia;School of Health Science,Faculty of Medicine and Health,The University of Sydney,Sydney,NSW,Australia ^[1] Department of Neonatology,Westmead Hospital,Westmead,NSW,Australia;The Reproduction and Perinatal Centre,Faculty of Medicine and Health,The University of Sydney,Sydney,NSW,Australia ^[2] Department of Neonatology,Westmead Hospital,Westmead,NSW,Australia;School of Nursing and Midwifery,Western Sydney University,Penrith,NSW,Australia ^[3] Miracle Babies Foundation,Moorebank,NSW,Australia ^[4] Mercy Perinatal,The Mercy Hospital for Women,Melbourne,VIC,Australia;Department of Obstetrics,Gynaecology and Newborn Health,The University of Melbourne,Melbourne,VIC,Australia;Murdoch Children's Research Institute,Melbourne,VIC,Australia ^[5] National Health and Medical Research Council Clinical Trials Centre,University of Sydney,Camperdown,NSW,Australia ^[6]

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Editorials

DOI 10.1007/s12519-025-00922-6

发布时间 2025-08-04（万方平台首次上网日期，不代表论文的发表时间）

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