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首页 > 世界儿科杂志（英文版） > Advances in magnetic resonance imaging of the developing brain and its applications in pediatrics

Advances in magnetic resonance imaging of the developing brain and its applications in pediatrics

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摘要The human brain undergoes a complex and dynamic developmental process from birth through adolescence,driven by molecular and cellular mechanisms that shape its structure and function.Magnetic resonance imaging(MRI)has become an essential non-invasive tool for studying pediatric brain development and detecting neurological disorders.However,pediatric neuroimaging presents unique challenges,including motion artifacts,small anatomical structures,and immature tissue properties,necessitating specialized MRI techniques.This review provides an overview of recent advancements in MRI hardware,acquisition strategies,and analytical methods optimized for pediatric brain imaging.Furthermore,it sum-marizes the applications of these techniques in understanding normal brain development,neurodevelopmental disorders,and the impact of early-life risk factors.This review highlights the progresses in pediatric MRI,emphasizing its critical role in advancing our understanding of pediatric brain development and neurological health.It also outlines the challenges and future directions in pediatric MRI to further improve imaging precision and clinical utility.

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作者 Rui-Ke Chen [1] Ming-Yang Li [2] Zhi-Yong Zhao [3] Hao-An Xu [1] Cheng-Lin Ning [1] Jie Lu [1] Qin-Feng Zhu [1] Yong-Quan Huang [1] Ruo-Ke Zhao [1] Ling-Xuan Zhang [1] Tian-Li Tao [4] Kai-Bo Tang [5] Jia-Le Cheng [5] Can Lai [3] Hong-Xi Zhang [3] Xiao-Hui Ma [3] Hosung Kim [6] Zhi-Hua Ren [4] Chun-Feng Lian [7] Fan Wang [8] Geng Chen [9] Min-Hui Ouyang [10] An-Qi Qiu [11] Han Zhang [12] Xiao-Qi Huang [13] Xu-Jun Duan [14] Gang Li [5] Jian Yang [15] Hao Huang [10] Kenichi Oishi [16] Ellen Grant [17] Wei-Li Lin [18] Duan Xu [19] Dan Wu [20] 学术成果认领
作者单位 Key Laboratory for Biomedical Engineering of Ministry of Education,Zhejiang University College of Biomedical Engineering and Instrument Science,Hangzhou 310027,China [1] Key Laboratory for Biomedical Engineering of Ministry of Education,Zhejiang University College of Biomedical Engineering and Instrument Science,Hangzhou 310027,China;Children's Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Zhejiang University,Hangzhou 310003,China [2] Children's Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Zhejiang University,Hangzhou 310003,China [3] School of Biomedical Engineering and State Key Laboratory of Advanced Medical Materials and Devices,ShanghaiTech University,Shanghai,China [4] Department of Radiology and Biomedical Research Imaging Center,University of North Carolina at Chapel Hill,Chapel Hill,NC 27599,USA [5] USC Stevens Neuroimaging and Informatics Institute,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA 90033,USA [6] School of Mathematics and Statistics,Xi'an Jiaotong University,Xi'an,China [7] The Key Laboratory of Biomedical Information Engineering of Ministry of Education,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an,China [8] National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology,School of Computer Science and Engineering,Northwestern Polytechnical University,Xi'an,China [9] Department of Radiology,Perelman School of Medicine,University of Pennsylvania,Philadelphia,PA,USA [10] Department of Health Technology and Informatics,The Hong Kong Polytechnic University,Hung Hom,Hong Kong [11] School of Biomedical Engineering and State Key Laboratory of Advanced Medical Materials and Devices,ShanghaiTech University,Shanghai,China;Shanghai Clinical Research and Trial Center,Shanghai 201210,China [12] Department of Radiology,Huaxi MR Research Center(HMRRC),Institution of Radiology and Medical Imaging,West China Hospital of Sichuan University,Chengdu,Sichuan,China [13] The Clinical Hospital of Chengdu Brain Science Institute,School of Life Science and Technology,University of Electronic Science and Technology of China,Chengdu 610054,People's Republic of China [14] Department of Psychiatry,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,China [15] Department of Radiology,Johns Hopkins University,Baltimore,MD,USA [16] Fetal-Neonatal Neuroimaging and Developmental Science Center,Division of Newborn Medicine,Department of Medicine,Boston Children's Hospital,Harvard Medical School,Boston,MA,USA [17] Department of Radiology,University of North Carolina at Chapel Hill,Chapel Hill,NC,USA [18] Department of Radiology and Biomedical Imaging,University of California San Francisco,San Francisco,CA,USA [19] Key Laboratory for Biomedical Engineering of Ministry of Education,Zhejiang University College of Biomedical Engineering and Instrument Science,Hangzhou 310027,China;Zhejiang University,Room 525,Zhou Yiqing Building,Yuquan Campus,Hangzhou 310058,China [20]
关键词 Brain developmentMagnetic resonance imagingNeuroimagingNeurological disordersPediatrics
栏目名称
Review articles
DOI 10.1007/s12519-025-00905-7
发布时间 2025-08-25（万方平台首次上网日期，不代表论文的发表时间）
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世界儿科杂志（英文版）

世界儿科杂志（英文版）

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世界儿科杂志（英文版）

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2025年21卷7期

652-707页

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