摘要Three-dimensional(3D)printing has revolutionized the design and production of customized scaffolds,but the minimally in-vasive implantation of 3D-printed structures into the human body remains challenging.This has prompted the exploration of innovative materials and technical solutions.Shape-memory polymers,as advanced intelligent materials,exhibit considerable potential in minimally invasive surgical applications.Herein,we developed a novel thermosetting shape-memory polymer,poly(L-lactic acid)-trimethylene carbonate-glycolic acid(PLLA-TMC-GA),for the fabrication of bioengineered scaffolds with body temperature-activated shape-memory functionality.We comprehensively evaluated the mechanical properties,thermal stability,shape-memory capabilities,biocompatibility,biodegradability,and 3D printing performance of PLLA-TMC-GA terpolymers with various compositions.The results indicate that PLLA-TMC-GA exhibits exceptional shape-memory perfor-mance,adjustable material properties,favorable biocompatibility,and the potential for controlled biodegradation and reab-sorption.The use of PLLA-TMC-GA as a biodegradable shape-memory polymer allows the reduction of implant volume,simplifies implantation,and enables on-demand activation at body temperature.These characteristics present new opportuni-ties for the advancement of minimally invasive surgical techniques.