摘要研究目的:探讨小儿癫痫与免疫的关系以及免疫制剂对小儿癫痫的治疔效果。研究方法:59例癫痫患儿,男37例,女22例。采用单向免疫扩散法检测血中IgG、IgM、IgA和补体C 3、C 4。用人丙种球蛋白肌注治疗小儿癫痫。 研究结果:71.19%的患儿IgA<1.40g/L, 30.15%的患者IgG<8.0g/L,部分患儿存在着低补体血症。采用人丙种球蛋白治疗小儿癫痫,总有效率达81.36%。研究结论:小儿癫痫患者存在着免疫异常,免疫异常可能是小儿癫痫发病的重要原因之一。用人丙种球蛋白治疗小儿癫痫有效。
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abstractsObjectives:To search for the relationship between child epilepsia patients and immunity, and the therapeutic effects of immune agent for epilepsia.Methods:Fifty—nine child patients with epilepsia, 37 males and 22 females. IgG、IgM、IgA、C 3 and C 4 were determined by single radial immunodiffusion test. The human gamma—globulin were used to treat epilepsia. Results:The level of the IgA dccrcase under 1.40g/L in 42 patients (71.19%) ,the level of the IgG decrease under 8.0g/L in 18 patients (30.15%) ,There is hypocomplementemia in some of the child patients. The total effective rate treated by human gammaglobulin is 81.36%.Conclusions:There is abnormal immunologic function in the child patients with epilepsia. Abnormal immunolo gic function may be one of the important reasons.lt's effective that use human gamma-globulin to treat child patients with epilepsia.
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