摘要研究目的:探讨小儿肾脏疾病血清补体对免疫沉淀的抑制作用（IIPC）及IIPC的低下情况。研究方法:急性肾小球肾炎23例，慢性肾小球肾炎25例，肾病综合征30例，对照组20例。以PO和抗-PO作为免疫沉淀中的抗原和抗体，用光电比色法测定患者血清IIPC。结果:正常对照IIPC OD为0.505±0.085，急性肾小球肾炎（0.137±0.108）显著降低（ P<0.001）；慢性肾小球肾炎（0.470±0.053）改变不明显（ P>0.05）；肾病综合征（0.401 ±0.038）明显低下（ P<0.05）。IIPC低下的发生率依次为急性肾小球肾炎（83%），肾病综合征（43%），慢性肾小球肾炎（32%）。 结论:IIPC在急性肾小球肾炎和肾病综合征中明显降低，慢性肾小球肾炎改变不明显，表明IIPC与肾小球疾病有一定关系。

abstractsObjectrves:To search for the inhibition of immune precipitation by complement (IIPC) of kidney disease in children and relationship of the lower IIPC and kidney disease.Methods:Twenty-three cases of children with acute glomerulonephritis (GN) , 25 chronic GN, 30 nephrotic syndrome and 20 normal children. Using peroxidase (PO) and an'i-PO as antigen and antibody of immune precipitation, serum IIPC were determined by photoelectric colormeter.Results:The OD valume of IIPC was 0.505±0.085 in normal individuals, IIPC of acute GN (0.137± 0.108) was markedly low ( P<0.001) , chronic GN (0.470±0.053) did no. change ( p>0.05) , nephrotic syndrome (0.401±0.038) was significantly decreased ( p<0.05) . The rates of lower IIPC were 83% in acute GN, 43% in nephrotic syndrome and 32? in chronic GN. Conclosion:IIPC were significant decrease in acute GN and nephrotic syndrome, IIPC of chronic GN did not marked change. These results suggest that the change of IIPC is related to activity of kidney diseases.