摘要癫(癎)性脑病为癫(癎)性异常本身引起的进行性脑功能障碍,主要包括起病于新生儿早期的早期肌阵挛脑病和大田原综合征,起病于婴儿期的West综合征和Dravet综合征,起病于婴儿和儿童早期的非进展性脑病中的肌阵挛持续状态,起病于儿童与青少年时期的Lennox-Gastaut综合征、Landau-Kleffner综合征和癫(癎)伴慢波睡眠期持续棘慢波.随着研究的深入,婴儿游走性局限性癫(癎)和伴多个独立棘波灶的严重癫(癎)也被推荐归纳入癫(癎)性脑病的范畴.现对癫(癎)性脑病的临床、病因、脑电图特点、治疗及预后进行综述.

abstractsEpileptic encephalopathies are an epileptic condition characterized by epileptiform abnormalities associated with progressive cerebral dysfunction.These syndromes include early myoclonic encephalopathy and Ohtahara syndrome in the neonatal period,West syndrome and Dravet syndrome in infancy,myoclonic status in nonprogressive encephalopathies,and Lennox-Gastaut syndrome,Landau-Kleffner syndrome,and epilepsy with continuous spike waves during slow wave sleep in childhood and adolescences.Other epileptic syndromes such as migrating partial seizures in infancy and severe epilepsy with multiple independent spike foci may be reasonably added.In this paper,an overview of epileptic encephalopathies including clinical features,etiology,electroencephalogram characteristics,treatment and prognosis are provided.