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胎儿先天性支气管囊肿围生期的诊断与治疗

Perinatal diagnosis and treatment of congenital bronchogenic cysts in infants

摘要目的:讨论胎儿先天性支气管囊肿的诊断和早期干预治疗。方法回顾性分析广东省妇幼保健院2013年1月至2014年5月诊断为胎儿先天性支气管囊肿7例患儿的临床特征,结合出生后 CT 以及手术、病理检查,分析胎儿先天性支气管囊肿的产前诊断和出生后的治疗经验。结果在胎儿产前超声影像和出生后 CT 及手术病理的基础上,共有7例支气管囊肿患儿得到确诊。其中4例产前诊断为肺囊腺瘤,3例产前诊断为胎儿支气管囊肿,产前超声诊断准确率为42.9%(3/7例)。出生后行 CT 检查并手术,7例均经胸腔入路行囊肿切除,手术年龄为(5.3±1.7)个月。手术方式分别为支气管囊肿切除4例,支气管囊肿+肺囊腺瘤切除2例,支气管囊肿+隔离肺切除1例。术中确诊支气管囊肿4例,合并先天性肺囊腺瘤2例,合并先天性肺隔离症1例。出生后 CT 诊断准确率为85.7%(6/7例)。所有手术治疗患儿均治愈。结论胎儿支气管囊肿多伴肺部先天性畸形,产前诊断胎儿支气管囊肿存在一定困难,尤其需要与肺囊腺瘤鉴别,为避免出现压迫、感染症状,产前诊断+出生后 CT 检查+早期手术的治疗模式是值得推荐的诊疗模式。

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abstractsObjective To discuss the diagnosis and early intervention treatment of fetal congenital broncho-genic cysts based on the cases reviewed. Methods The clinical features of 7 infants presenting bronchogenic cysts diagnosed antenatally from January 2013 to May 2014 in Guangdong Women and Children's Hospital and Health In-stitute were reviewed retrospectively. Pathology,the prenatal diagnosis and treatment of bronchogenic cysts experience were summarized combined with CT after birth and surgery. Results Based on the prenatal diagnosis of fetal and postnatal CT and surgical pathology,a total of 7 cases with congenital bronchial cysts were diagnosed. Of which 4 ca-ses were suggestive of congenital cystsic adenomatoid malformation by prenatal diagnosis,and the other 3 cases had fetal bronchial cysts by prenatal diagnosis,antenatal diagnosis was accurate in 42. 9%(3 / 7 cases). CT examinations were taken in 7 cases after birth,and the cyst excision was performed on them with surgery thoracic approach;the average age at surgery was(5. 3 ± 1. 7)months. Four cases had simple bronchial cystss,2 cases with congenital cystsic adenomatoid malformation,1 case with congenital pulmonary sequestration. The accuracy of CT diagnosis was 85. 7%(6 / 7 cases). All surgical treatment was effective. Conclusions Fetal bronchial cysts is always associated with the other presence of lung congenital malformations. Prenatal diagnosis of congenital bronchial cysts is difficult. Prenatal diagnosis is difficult to exclude congenital cystsic adenomatoid malformation. To avoid symptoms like oppres-sion,infection,prenatal diagnosis combined with CT examination after birth and early treatment are necessary and reliable clinically.

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中华实用儿科临床杂志

中华实用儿科临床杂志

2015年14期

1076-1079页

ISTICPKUCSCDCA

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